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BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini
NAR
2006
82views more  NAR 2006»
13 years 7 months ago
PROFtmb: a web server for predicting bacterial transmembrane beta barrel proteins
PROFtmb predicts transmembrane beta-barrel (TMB) proteins in Gram-negative bacteria. For each query protein, PROFtmb provides both a Z-value indicating that the protein actually c...
Henry R. Bigelow, Burkhard Rost
BMCBI
2011
13 years 2 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
RECOMB
2009
Springer
14 years 8 months ago
Learning Models for Aligning Protein Sequences with Predicted Secondary Structure
Accurately aligning distant protein sequences is notoriously difficult. A recent approach to improving alignment accuracy is to use additional information such as predicted seconda...
Eagu Kim, Travis J. Wheeler, John D. Kececioglu
IPPS
2008
IEEE
14 years 2 months ago
Adaptive Locality-Effective Kernel Machine for protein phosphorylation site prediction
In this study, we propose a new machine learning model namely, Adaptive Locality-Effective Kernel Machine (Adaptive-LEKM) for protein phosphorylation site prediction. Adaptive-LEK...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...