—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
One of the aims of modern Bioinformatics is to discover the molecular mechanisms that rule the protein operation. This would allow us to understand the complex processes involved i...
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
We present a new unsupervised algorithm for training structured predictors that is discriminative, convex, and avoids the use of EM. The idea is to formulate an unsupervised versi...
Linli Xu, Dana F. Wilkinson, Finnegan Southey, Dal...
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...