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IPPS
2006
IEEE
14 years 1 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan
AIIA
2007
Springer
13 years 11 months ago
Advanced Tree-Based Kernels for Protein Classification
One of the aims of modern Bioinformatics is to discover the molecular mechanisms that rule the protein operation. This would allow us to understand the complex processes involved i...
Elisa Cilia, Alessandro Moschitti
BIBM
2007
IEEE
104views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
A Protocol to Detect Local Affinities Involved in Proteins Distant Interactions
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
Christophe Nicolas Magnan, Cécile Capponi, ...
ICML
2006
IEEE
14 years 8 months ago
Discriminative unsupervised learning of structured predictors
We present a new unsupervised algorithm for training structured predictors that is discriminative, convex, and avoids the use of EM. The idea is to formulate an unsupervised versi...
Linli Xu, Dana F. Wilkinson, Finnegan Southey, Dal...
BMCBI
2008
94views more  BMCBI 2008»
13 years 7 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...