472 search results - page 44 / 95 » Local protein structure prediction using discriminative mode... |
BMCBI
2007
13 years 9 months ago
2007
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
BMCBI
2010
13 years 9 months ago
2010
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
BIOINFORMATICS
2010
13 years 9 months ago
2010
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
BMCBI
2010
13 years 9 months ago
2010
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...
NIPS
2008
13 years 10 months ago
2008
Probabilistic topic models have become popular as methods for dimensionality reduction in collections of text documents or images. These models are usually treated as generative m...