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BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2007
143views more  BMCBI 2007»
13 years 10 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos
BMCBI
2008
95views more  BMCBI 2008»
13 years 10 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2007
176views more  BMCBI 2007»
13 years 10 months ago
Correlation-maximizing surrogate gene space for visual mining of gene expression patterns in developing barley endosperm tissue
Background: Micro- and macroarray technologies help acquire thousands of gene expression patterns covering important biological processes during plant ontogeny. Particularly, fait...
Marc Strickert, Nese Sreenivasulu, Björn Usad...
CCR
2008
84views more  CCR 2008»
13 years 10 months ago
Modeling internet topology dynamics
Despite the large number of papers on network topology modeling and inference, there still exists ambiguity about the real nature of the Internet AS and router level topology. Whi...
Hamed Haddadi, Steve Uhlig, Andrew W. Moore, Richa...