Optimized spaced seeds improve sensitivity and specificity in local homology search. Several authors have shown that multiple seeds can have better sensitivity and specificity t...
Background: We have developed the program PERMOL for semi-automated homology modeling of proteins. It is based on restrained molecular dynamics using a simulated annealing protoco...
We consider coverage problems in sensor networks of stationary nodes with minimal geometric data. In particular, there are no coordinates and no localization of nodes. We introduc...
ABSTRACT. We introduce tools from computational homology to verify coverage in an idealized sensor network. Our methods are unique in that, while they are coordinate-free and assum...
Homologousproteins do not necessarily exhibit identical biochemicalfunction. Despitethis fact, local or global sequence similarity is widely used as an indication of functional id...