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BMCBI
2005
133views more  BMCBI 2005»
15 years 3 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BMCBI
2005
115views more  BMCBI 2005»
15 years 3 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner
BMCBI
2005
102views more  BMCBI 2005»
15 years 3 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
BMCBI
2005
157views more  BMCBI 2005»
15 years 3 months ago
Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome bro
Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotat...
Judith E. Stenger, Hong Xu, Carol Haynes, Elizabet...
TMI
2008
126views more  TMI 2008»
15 years 3 months ago
A Time Domain Fluorescence Tomography System for Small Animal Imaging
We describe the application of a time domain diffuse fluorescence tomography system for whole body small animal imaging. The key features of the system are the use of point excitat...
Anand T. N. Kumar, Scott B. Raymond, Andrew K. Dun...
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