Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome bro

Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotation tools are essential to integrate, visualize and analyze vast quantities of disparate data generated by genomic screens, public human genome sequence annotation and ancillary biological databases. We have developed a plug-in package for Ensembl called "Statistical Viewer" that facilitates the analysis of genomic features and annotation in the regions of interest defined by linkage analysis. Results: Statistical Viewer is an add-on package to the open-source Ensembl Genome Browser and Annotation System that displays disease study-specific linkage and/or association data as 2 dimensional plots in new panels in the context of Ensembl's Contig View and Cyto View pages. An enhanced upload server facilitates the upload of statistical data, as well as additional feature annotation to be displayed i...

• Type: Journal
• Year: 2005
• Where: BMCBI
• Authors: Judith E. Stenger, Hong Xu, Carol Haynes, Elizabeth R. Hauser, Margaret A. Pericak-Vance, Pascal J. Goldschmidt-Clermont, Jeffery M. Vance
• Keywords: Annotation, Annotation System, BMCBI 2005, Statistical Viewer