Sciweavers

243 search results - page 15 / 49
» Logic-Statistic Models with Constraints for Biological Seque...
Sort
View
ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
AAAI
2007
13 years 10 months ago
A Randomized String Kernel and Its Application to RNA Interference
String kernels directly model sequence similarities without the necessity of extracting numerical features in a vector space. Since they better capture complex traits in the seque...
Shibin Qiu, Terran Lane, Ljubomir J. Buturovic
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
RECOMB
2004
Springer
14 years 8 months ago
Structured motifs search
In this paper we describe an algorithm for the localization of structured models, i.e. sequences of (simple) motifs and distance constraints. It basically combines standard patter...
Alberto Policriti, Nicola Vitacolonna, Michele Mor...
NAR
2008
152views more  NAR 2008»
13 years 7 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin