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BMCBI
2007
143views more  BMCBI 2007»
13 years 7 months ago
Gene selection for classification of microarray data based on the Bayes error
Background: With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a critical step for accurate classification of phenotypes for, ...
Ji-Gang Zhang, Hong-Wen Deng
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
EJIS
2010
52views more  EJIS 2010»
13 years 7 months ago
Same technology, different outcome? Reinterpreting Barley's Technology as an Occasion for Structuring
In the last few decades, several studies have found the same technology implemented in highly similar organizational settings to be associated with very different consequences for...
Starling David Hunter III
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...