Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...
Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam...
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...