MannDB - A microbial database of automated protein sequence analyses and evidence integration for protein characterization

Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the development of reagents for pathogen or protein toxin detection. Because a large number of open-source tools were needed, it was necessary to produce a software system to scale the computations for whole-proteome analysis. Thus, we built a fully automated system for executing software tools and for storage, integration, and display of automated protein sequence analysis and annotation data. Description: MannDB is a relational database that organizes data resulting from fully automated, highthroughput protein-sequence analyses using open-source tools. Types of analyses provided include predictions of cleavage, chemical properties, classification, features, functional assignment, post-translational modifications, motifs, antigenicity, and secondary structure. Proteomes (lists of hypothetical and known proteins) ar...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam Zemla, Matthew D. Dyer, Thomas A. Kuczmarski, Elizabeth A. Vitalis, Thomas R. Slezak
• Keywords: BMCBI 2006, Open-source Tools, Protein, Protein Sequence