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BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
BMCBI
2007
133views more  BMCBI 2007»
13 years 7 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2010
155views more  BMCBI 2010»
13 years 7 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2010
190views more  BMCBI 2010»
13 years 7 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...