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149
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BMCBI
2004
123views more  BMCBI 2004»
15 years 4 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
175
Voted
BMCBI
2004
144views more  BMCBI 2004»
15 years 4 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BMCBI
2004
150views more  BMCBI 2004»
15 years 4 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
184
Voted
BMCBI
2004
110views more  BMCBI 2004»
15 years 4 months ago
Tools for loading MEDLINE into a local relational database
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...
Diane E. Oliver, Gaurav Bhalotia, Ariel S. Schwart...
BMCBI
2004
100views more  BMCBI 2004»
15 years 4 months ago
Handling multiple testing while interpreting microarrays with the Gene Ontology Database
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...
Michael V. Osier, Hongyu Zhao, Kei-Hoi Cheung
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