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BMCBI
2010
13 years 7 months ago
2010
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
BMCBI
2010
13 years 7 months ago
2010
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
BMCBI
2010
13 years 7 months ago
2010
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
BMCBI
2010
13 years 7 months ago
2010
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
BMCBI
2010
13 years 7 months ago
2010
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...