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» Massively-Parallel Simulation of Biochemical Systems
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BMCBI
2010
126views more  BMCBI 2010»
13 years 5 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
CDC
2010
IEEE
161views Control Systems» more  CDC 2010»
13 years 2 months ago
Circadian system modeling and phase control
Circadian rhythms are biological processes found in all living organisms, from plants to insects to mammals that repeat with a period close to, but not exactly, 24 hours. In the ab...
Jiaxiang Zhang, Andrew Bierman, John T. Wen, Agung...
ISCA
2007
IEEE
196views Hardware» more  ISCA 2007»
14 years 2 months ago
Anton, a special-purpose machine for molecular dynamics simulation
The ability to perform long, accurate molecular dynamics (MD) simulations involving proteins and other biological macromolecules could in principle provide answers to some of the ...
David E. Shaw, Martin M. Deneroff, Ron O. Dror, Je...
CDC
2009
IEEE
124views Control Systems» more  CDC 2009»
14 years 17 days ago
Design of insulating devices for in vitro synthetic circuits
— This paper describes a synthetic in vitro genetic circuit programmed to work as an insulating device. This circuit is composed of nucleic acids, which can be designed to intera...
Elisa Franco, Domitilla Del Vecchio, Richard M. Mu...
ISMB
1998
13 years 9 months ago
BioSim: A New Qualitative Simulation Environment for Molecular Biology
Traditionally, biochemical systems are modelled usingkinetics anddifferential equationsin a quantitative simulator. However,for manybiological processes detailed quantitative info...
Karsten R. Heidtke, Steffen Schulze-Kremer