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BMCBI
2007
117views more  BMCBI 2007»
13 years 8 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BMCBI
2010
89views more  BMCBI 2010»
13 years 8 months ago
Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
Background: Tissue MicroArray technology aims to perform immunohistochemical staining on hundreds of different tissue samples simultaneously. It allows faster analysis, considerab...
Federica Viti, Ivan Merelli, Mieke Timmermans, Mic...
BMCBI
2008
160views more  BMCBI 2008»
13 years 8 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
BMCBI
2008
137views more  BMCBI 2008»
13 years 8 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...
BMCBI
2008
115views more  BMCBI 2008»
13 years 8 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...