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BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
ICMCS
2006
IEEE
192views Multimedia» more  ICMCS 2006»
14 years 1 months ago
Classifier Optimization for Multimedia Semantic Concept Detection
In this paper, we present an AUC (i.e., the Area Under the Curve of Receiver Operating Characteristics (ROC)) maximization based learning algorithm to design the classifier for ma...
Sheng Gao, Qibin Sun
IJPRAI
2010
151views more  IJPRAI 2010»
13 years 6 months ago
Structure-Embedded AUC-SVM
: AUC-SVM directly maximizes the area under the ROC curve (AUC) through minimizing its hinge loss relaxation, and the decision function is determined by those support vector sample...
Yunyun Wang, Songcan Chen, Hui Xue
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
GCB
2004
Springer
126views Biometrics» more  GCB 2004»
14 years 28 days ago
Proteochemometrics Modeling of Receptor-Ligand Interactions Using Rough Sets
Abstract: We report on a model for the interaction of chimeric melanocortin Gprotein coupled receptors with peptide ligands using the rough set approach. Rough sets generate If-The...
H. Strömbergsson, Peteris Prusis, Herman Mide...