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» Maximum entropy methods for biological sequence modeling
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NIPS
2007
13 years 10 months ago
Adaptive Embedded Subgraph Algorithms using Walk-Sum Analysis
We consider the estimation problem in Gaussian graphical models with arbitrary structure. We analyze the Embedded Trees algorithm, which solves a sequence of problems on tractable...
Venkat Chandrasekaran, Jason K. Johnson, Alan S. W...
BMCBI
2004
87views more  BMCBI 2004»
13 years 9 months ago
prot4EST: Translating Expressed Sequence Tags from neglected genomes
Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
James Wasmuth, Mark L. Blaxter
BMCBI
2007
179views more  BMCBI 2007»
13 years 9 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2006
137views more  BMCBI 2006»
13 years 9 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2005
97views more  BMCBI 2005»
13 years 9 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg