Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
The usefulness of the results produced by data mining methods can be critically impaired by several factors such as (1) low quality of data, including errors due to contamination, ...
Fang Chu, Yizhou Wang, Carlo Zaniolo, Douglas Stot...
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
The combination of fully sequence genomes and new technologies for high density arrays and ultra-rapid sequencing enables the mapping of generegulatory and epigenetics marks on a g...