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» Maximum entropy methods for biological sequence modeling
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BMCBI
2007
167views more  BMCBI 2007»
13 years 9 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2010
87views more  BMCBI 2010»
13 years 9 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2005
140views more  BMCBI 2005»
13 years 9 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
GECCO
2007
Springer
189views Optimization» more  GECCO 2007»
14 years 29 days ago
A genetic algorithm with exon shuffling crossover for hard bin packing problems
A novel evolutionary approach for the bin packing problem (BPP) is presented. A simple steady-state genetic algorithm is developed that produces results comparable to other approa...
Philipp Rohlfshagen, John A. Bullinaria
BMCBI
2005
104views more  BMCBI 2005»
13 years 9 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...