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BMCBI
2006
118views more  BMCBI 2006»
13 years 11 months ago
Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
BMCBI
2007
86views more  BMCBI 2007»
13 years 11 months ago
Tandem mass spectrometry data quality assessment by self-convolution
Background: Many algorithms have been developed for deciphering the tandem mass spectrometry (MS) data sets. They can be essentially clustered into two classes. The first performs...
Keng Wah Choo, Wai Mun Tham
BMCBI
2005
145views more  BMCBI 2005»
13 years 11 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang
BMCBI
2004
131views more  BMCBI 2004»
13 years 11 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2004
139views more  BMCBI 2004»
13 years 11 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend