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BMCBI
2010
74views more  BMCBI 2010»
13 years 10 months ago
A weighted q-gram method for glycan structure classification
Background: Glycobiology pertains to the study of carbohydrate sugar chains, or glycans, in a particular cell or organism. Many computational approaches have been proposed for ana...
Limin Li, Wai-Ki Ching, Takako Yamaguchi, Kiyoko F...
BMCBI
2010
227views more  BMCBI 2010»
13 years 10 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2010
124views more  BMCBI 2010»
13 years 10 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2007
106views more  BMCBI 2007»
13 years 10 months ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...
BMCBI
2010
243views more  BMCBI 2010»
13 years 10 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...