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» Measuring complexity by measuring structure and organization
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152
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BMCBI
2010
96views more  BMCBI 2010»
15 years 6 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
161
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BMCBI
2008
188views more  BMCBI 2008»
15 years 6 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
RECOMB
2008
Springer
16 years 6 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
RECOMB
2004
Springer
16 years 6 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
COSIT
2009
Springer
159views GIS» more  COSIT 2009»
16 years 20 days ago
Adaptable Path Planning in Regionalized Environments
Human path planning relies on several more aspects than only geometric distance between two locations. These additional aspects mostly relate to the complexity of the traveled path...
Kai-Florian Richter