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BMCBI
2007
115views more  BMCBI 2007»
13 years 9 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
BMCBI
2007
147views more  BMCBI 2007»
13 years 9 months ago
Modeling biochemical transformation processes and information processing with Narrator
Background: Software tools that model and simulate the dynamics of biological processes and systems are becoming increasingly important. Some of these tools offer sophisticated gr...
Johannes J. Mandel, Hendrik Fuß, Niall M. Pa...
BMCBI
2007
124views more  BMCBI 2007»
13 years 9 months ago
CRISPR Recognition Tool (CRT): a tool for automatic detection of clustered regularly interspaced palindromic repeats
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct repeat found in a wide range of bacteria and archaea. CRISPRs are beginning to...
Charles Bland, Teresa L. Ramsey, Fareedah Sabree, ...
BMCBI
2007
179views more  BMCBI 2007»
13 years 9 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
BMCBI
2007
247views more  BMCBI 2007»
13 years 9 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai