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BMCBI
2005
13 years 9 months ago
2005
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
BMCBI
2005
13 years 9 months ago
2005
Background: Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a mechanism for allowing e...
BMCBI
2005
13 years 9 months ago
2005
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
BMCBI
2005
13 years 9 months ago
2005
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
13 years 9 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...