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BMCBI
2008
13 years 10 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
BMCBI
2008
13 years 10 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
BMCBI
2008
13 years 10 months ago
2008
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
BMCBI
2008
13 years 10 months ago
2008
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
BMCBI
2008
13 years 10 months ago
2008
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...