We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to...
Onureena Banerjee, Laurent El Ghaoui, Alexandre d'...
Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As biomolecular...
Xiaohua Hu, Fang-Xiang Wu, Michael K. Ng, Bahrad A...
Background: Very often genome-wide data analysis requires the interoperation of multiple databases and analytic tools. A large number of genome databases and bioinformatics applic...
Remko de Knikker, Youjun Guo, Jin-long Li, Albert ...
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...