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» Meta-classification of Multi-type Cancer Gene Expression Dat...
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NAR
2008
141views more  NAR 2008»
13 years 7 months ago
MethyCancer: the database of human DNA methylation and cancer
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
Ximiao He, Suhua Chang, Jiajie Zhang, Qian Zhao, H...
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
BMCBI
2006
122views more  BMCBI 2006»
13 years 7 months ago
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
Carmen Lai, Marcel J. T. Reinders, Laura J. van't ...
BMCBI
2007
112views more  BMCBI 2007»
13 years 7 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...