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RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
KDD
2001
ACM
169views Data Mining» more  KDD 2001»
14 years 8 months ago
Hierarchical cluster analysis of SAGE data for cancer profiling
In this paper we present a method for clustering SAGE (Serial Analysis of Gene Expression) data to detect similarities and dissimilarities between different types of cancer on the...
Jörg Sander, Monica C. Sleumer, Raymond T. Ng
BMCBI
2007
149views more  BMCBI 2007»
13 years 7 months ago
A unified framework for finding differentially expressed genes from microarray experiments
Background: This paper presents a unified framework for finding differentially expressed genes (DEGs) from the microarray data. The proposed framework has three interrelated modul...
Jahangheer S. Shaik, Mohammed Yeasin
BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Response projected clustering for direct association with physiological and clinical response data
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
Sung-Gon Yi, Taesung Park, Jae K. Lee
BMCBI
2004
117views more  BMCBI 2004»
13 years 7 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...