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BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Predicting survival outcomes using subsets of significant genes in prognostic marker studies with microarrays
Background: Genetic markers hold great promise for refining our ability to establish precise prognostic prediction for diseases. The development of comprehensive gene expression m...
Shigeyuki Matsui
ICML
2009
IEEE
14 years 8 months ago
Group lasso with overlap and graph lasso
We propose a new penalty function which, when used as regularization for empirical risk minimization procedures, leads to sparse estimators. The support of the sparse vector is ty...
Laurent Jacob, Guillaume Obozinski, Jean-Philippe ...
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
BMCBI
2011
13 years 2 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
NAR
2011
277views Computer Vision» more  NAR 2011»
12 years 10 months ago
The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection
The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes ...
Michael Y. Galperin, Guy Cochrane