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» Methods for Predicting Target Sites of Transcription Factors
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IDA
2008
Springer
13 years 7 months ago
Transcription factor binding site recognition by regularity matrices based on the natural classification method
A principally new approach to the classifications of nucleotide sequences based on the "natural" classification concept is proposed. As a result of "natural" c...
Eugenii E. Vityaev, K. A. Lapardin, I. V. Khomiche...
BMCBI
2010
131views more  BMCBI 2010»
13 years 4 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom
RECOMB
2003
Springer
14 years 7 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
PRIB
2010
Springer
123views Bioinformatics» more  PRIB 2010»
13 years 5 months ago
Machine Learning Study of DNA Binding by Transcription Factors from the LacI Family
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
Gennady G. Fedonin, Mikhail S. Gelfand
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...