Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...