276 search results - page 39 / 56 » Methods for Predicting Target Sites of Transcription Factors |
BMCBI
2008
13 years 7 months ago
2008
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
BMCBI
2010
13 years 7 months ago
2010
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
BMCBI
2006
13 years 7 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
ICGA
1997
13 years 8 months ago
1997
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
BMCBI
2006
13 years 7 months ago
2006
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...