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» Methods for Predicting Target Sites of Transcription Factors
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FOGA
2011
12 years 10 months ago
Approximating the distribution of fitness over hamming regions
The distribution of fitness values across a set of states sharply influences the dynamics of evolutionary processes and heuristic search in combinatorial optimization. In this p...
Andrew M. Sutton, Darrell Whitley, Adele E. Howe
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
CVPR
2009
IEEE
15 years 2 months ago
Memory-based particle filter for face pose tracking robust under complex dynamics
A novel particle filter, the Memory-based Particle Filter (M-PF), is proposed that can visually track moving objects that have complex dynamics. We aim to realize robustness aga...
Dan Mikami (NTT), Kazuhiro Otsuka (NTT), Junji YAM...
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...