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BMCBI
2004
100views more  BMCBI 2004»
13 years 7 months ago
Handling multiple testing while interpreting microarrays with the Gene Ontology Database
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...
Michael V. Osier, Hongyu Zhao, Kei-Hoi Cheung
RECOMB
2004
Springer
14 years 8 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
CEC
2010
IEEE
13 years 9 months ago
Evolutionary layered hypernetworks for identifying microRNA-mRNA regulatory modules
Abstract-- Exploring microRNA (miRNA) and mRNA regulatory interactions may give new insights into diverse biological phenomena. While elucidating complex miRNA-mRNA interactions ha...
Soo-Jin Kim, JungWoo Ha, Bado Lee, Byoung-Tak Zhan...
BMCBI
2006
175views more  BMCBI 2006»
13 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
MICCAI
2010
Springer
13 years 6 months ago
Model-Free, Regularized, Fast, and Robust Analytical Orientation Distribution Function Estimation
High Angular Resolution Imaging (HARDI) can better explore the complex micro-structure of white matter compared to Diffusion Tensor Imaging (DTI). Orientation Distribution Functio...
Jian Cheng, Aurobrata Ghosh, Rachid Deriche, Tianz...