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BMCBI
2007
102views more  BMCBI 2007»
13 years 11 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
BMCBI
2007
142views more  BMCBI 2007»
13 years 11 months ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim
BMCBI
2007
152views more  BMCBI 2007»
13 years 11 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada
BMCBI
2007
218views more  BMCBI 2007»
13 years 11 months ago
Annotation and query of tissue microarray data using the NCI Thesaurus
Background: The Stanford Tissue Microarray Database (TMAD) is a repository of data serving a consortium of pathologists and biomedical researchers. The tissue samples in TMAD are ...
Nigam H. Shah, Daniel L. Rubin, Inigo Espinosa, Ke...
BMCBI
2007
186views more  BMCBI 2007»
13 years 11 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
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