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» Methods in biomedical ontology
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WSC
2007
13 years 11 months ago
Using ontologies for simulation integration
This paper describes the motivations, methods, and solution concepts for the use of ontologies for simulation model integration. Ontological analysis has been shown to be an effec...
Perakath C. Benjamin, Kumar V. Akella, Ajay Verma
BMCBI
2008
200views more  BMCBI 2008»
13 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2006
152views more  BMCBI 2006»
13 years 9 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
HIKM
2006
ACM
14 years 3 months ago
Epoch: an ontological framework to support clinical trials management
The increasing complexity of clinical trials has generated an enormous requirement for knowledge and information specification at all stages of the trials, including planning, doc...
Ravi D. Shankar, Susana B. Martins, Martin J. O'Co...