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BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Vector analysis as a fast and easy method to compare gene expression responses between different experimental backgrounds
Background: Gene expression studies increasingly compare expression responses between different experimental backgrounds (genetic, physiological, or phylogenetic). By focusing on ...
Rainer Breitling, Patrick Armengaud, Anna Amtmann
BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2007
182views more  BMCBI 2007»
13 years 7 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2011
13 years 2 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...