Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
A central challenge in systems biology is the reconstruction of biological networks from high-throughput data sets. A particularly difficult case of this is the inference of dynami...
Michael Baym, Chris Bakal, Norbert Perrimon, Bonni...