The goal of the knowledge discovery and data mining is to extract the useful knowledge from the given data. Visualization enables us to find structures, features, patterns, and re...
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...