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» Microarray results: how accurate are they
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BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
BMCBI
2008
98views more  BMCBI 2008»
13 years 10 months ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
BMCBI
2008
93views more  BMCBI 2008»
13 years 10 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
BMCBI
2007
120views more  BMCBI 2007»
13 years 9 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
BMCBI
2010
146views more  BMCBI 2010»
13 years 10 months ago
On the Choice and Number of Microarrays for Transcriptional Regulatory Network Inference
Background: Transcriptional regulatory network inference (TRNI) from large compendia of DNA microarrays has become a fundamental approach for discovering transcription factor (TF)...
Elissa J. Cosgrove, Timothy S. Gardner, Eric D. Ko...