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» Microarray results: how accurate are they
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BMCBI
2004
131views more  BMCBI 2004»
13 years 9 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2010
135views more  BMCBI 2010»
13 years 10 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2006
142views more  BMCBI 2006»
13 years 10 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2011
13 years 4 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
PODS
2002
ACM
154views Database» more  PODS 2002»
14 years 10 months ago
How to Evaluate Multiple Range-Sum Queries Progressively
Decision support system users typically submit batches of range-sum queries simultaneously rather than issuing individual, unrelated queries. We propose a wavelet based technique ...
Rolfe R. Schmidt, Cyrus Shahabi