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» Microarray results: how accurate are they
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BMCBI
2007
123views more  BMCBI 2007»
13 years 10 months ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
BMCBI
2010
148views more  BMCBI 2010»
13 years 10 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
BMCBI
2007
148views more  BMCBI 2007»
13 years 10 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
ACL
2008
13 years 11 months ago
Generating Impact-Based Summaries for Scientific Literature
In this paper, we present a study of a novel summarization problem, i.e., summarizing the impact of a scientific publication. Given a paper and its citation context, we study how ...
Qiaozhu Mei, ChengXiang Zhai
BMCBI
2010
94views more  BMCBI 2010»
13 years 10 months ago
A high-throughput pipeline for the design of real-time PCR signatures
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...