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BMCBI
2006
115views more  BMCBI 2006»
13 years 6 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
ICDE
2004
IEEE
133views Database» more  ICDE 2004»
14 years 8 months ago
GenExplore: Interactive Exploration of Gene Interactions from Microarray Data
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
BMCBI
2008
121views more  BMCBI 2008»
13 years 6 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
BMCBI
2007
130views more  BMCBI 2007»
13 years 6 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
CSB
2002
IEEE
169views Bioinformatics» more  CSB 2002»
13 years 11 months ago
Bayesian Network and Nonparametric Heteroscedastic Regression for Nonlinear Modeling of Genetic Network
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
Seiya Imoto, SunYong Kim, Takao Goto, Sachiyo Abur...