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BMCBI
2007
153views more  BMCBI 2007»
13 years 10 months ago
Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
Background: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel ...
Matthew Landry, Stephen Winters-Hilt
VLSISP
2011
358views Database» more  VLSISP 2011»
13 years 5 months ago
Accelerating Machine-Learning Algorithms on FPGAs using Pattern-Based Decomposition
Machine-learning algorithms are employed in a wide variety of applications to extract useful information from data sets, and many are known to suffer from superlinear increases in ...
Karthik Nagarajan, Brian Holland, Alan D. George, ...
ECML
2001
Springer
14 years 2 months ago
Classification on Data with Biased Class Distribution
Labeled data for classification could often be obtained by sampling that restricts or favors choice of certain classes. A classifier trained using such data will be biased, resulti...
Slobodan Vucetic, Zoran Obradovic
BMCBI
2006
134views more  BMCBI 2006»
13 years 10 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2007
127views more  BMCBI 2007»
13 years 10 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...