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BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...
KES
2008
Springer
13 years 7 months ago
Classification and Retrieval through Semantic Kernels
Abstract. This work proposes a family of language-independent semantic kernel functions defined for individuals in an ontology. This allows exploiting wellfounded kernel methods fo...
Claudia d'Amato, Nicola Fanizzi, Floriana Esposito
BMCBI
2011
12 years 11 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
ICCAD
2006
IEEE
147views Hardware» more  ICCAD 2006»
14 years 4 months ago
Analysis and modeling of CD variation for statistical static timing
Statistical static timing analysis (SSTA) has become a key method for analyzing the effect of process variation in aggressively scaled CMOS technologies. Much research has focused...
Brian Cline, Kaviraj Chopra, David Blaauw, Yu Cao
BMCBI
2006
152views more  BMCBI 2006»
13 years 8 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...