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» Mining Information for Functional Genomics
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TCBB
2011
14 years 11 months ago
Information-Theoretic Model of Evolution over Protein Communication Channel
—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
Liuling Gong, Nidhal Bouaynaya, Dan Schonfeld
KDD
2009
ACM
150views Data Mining» more  KDD 2009»
16 years 5 months ago
Information theoretic regularization for semi-supervised boosting
We present novel semi-supervised boosting algorithms that incrementally build linear combinations of weak classifiers through generic functional gradient descent using both labele...
Lei Zheng, Shaojun Wang, Yan Liu, Chi-Hoon Lee
PKDD
2010
Springer
177views Data Mining» more  PKDD 2010»
15 years 2 months ago
ITCH: Information-Theoretic Cluster Hierarchies
Hierarchical clustering methods are widely used in various scientific domains such as molecular biology, medicine, economy, etc. Despite the maturity of the research field of hie...
Christian Böhm, Frank Fiedler, Annahita Oswal...
BMCBI
2008
130views more  BMCBI 2008»
15 years 4 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2007
116views more  BMCBI 2007»
15 years 4 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...