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» Mining Phenotypes for Protein Function Prediction
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BMCBI
2004
229views more  BMCBI 2004»
13 years 7 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
ICDM
2009
IEEE
152views Data Mining» more  ICDM 2009»
14 years 2 months ago
SLIDER: Mining Correlated Motifs in Protein-Protein Interaction Networks
Correlated motif mining (CMM) is the problem to find overrepresented pairs of patterns, called motif pairs, in interacting protein sequences. Algorithmic solutions for CMM thereb...
Peter Boyen, Frank Neven, Dries Van Dyck, Aalt-Jan...
BMCBI
2005
95views more  BMCBI 2005»
13 years 7 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
PAKDD
2005
ACM
180views Data Mining» more  PAKDD 2005»
14 years 26 days ago
Conditional Random Fields for Transmembrane Helix Prediction
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Lior Lukov, Sanjay Chawla, W. Bret Church
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...