Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...
Alternative splicing (AS) is a major mechanism to generate protein diversity. A single gene might generate hundreds or even thousands of different proteins. Recently, powerful lar...
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...