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IWANN
2009
Springer
14 years 2 months ago
GREAT: Gene Regulation EvAluation Tool
Our understanding of biological systems is highly dependent on the study of the mechanisms that regulate genetic expression. In this paper we present a tool to evaluate scientific ...
Catia Machado, Hugo P. Bastos, Francisco M. Couto
BMCBI
2008
202views more  BMCBI 2008»
13 years 7 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2008
201views more  BMCBI 2008»
13 years 7 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
DMKD
2003
ACM
96views Data Mining» more  DMKD 2003»
14 years 24 days ago
Using transposition for pattern discovery from microarray data
We analyze expression matrices to identify a priori interesting sets of genes, e.g., genes that are frequently co-regulated. Such matrices provide expression values for given biol...
François Rioult, Jean-François Bouli...